SILICONE OIL AND COATING FREE PLUNGER STOPPERS

THE LUBRIGONE STOPPER COLLECTION

Lubrication in prefilled syringes can cause adverse effects on various pharmaceutical drugs, alter immunologic response and ultimately affect patient safety.

The lubrigone stopper enables prefilled syringes without lubricated or coated components.

Despite the elimination of lubrication lubrigone offers a high degree of user-friendliness during injection administration.

• Reduced risk of protein aggregation
• Compliant with glass or polymer (COC/COP)
• Low break-loose force

OUTSTANDING LUBRICATION FREE PERFORMANCE

lubrigone is a completely lubrication free, and coating free solution that provides container closure integrity and a low break loose force even after a long shelf life.

It is based on a special medical grade thermoplastic elastomer that combined with the special design provides excellent performance required for prefillable syringes.

It offers a completely lubrication free solution, hence the best way to protect pharmaceutical and biologic liquid injectables against potential adverse effects, such as the risk of protein aggregation.

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0.5 / 0.1 ML
GLASS & COC / COP
AUTO DISABLING

lubrigone1 Logo

0.5 / 0.1 ML
GLASS & COC / COP
SINGLE RIB

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0.5 / 0.1 ML
GLASS & COC / COP
DUAL RIB

DATASHEET

Would you like to know more…
Besides our data sheet, we have extensive test reports on extractables, container closure integrity, break loose and gliding forces.
Please send us a mail with information about your company, purpose and interest.

Existing prefillable syringe systems on the market predominantly use traditional stoppers, which have a strong adhesiveness towards especially glass but also polymer container materials, necessitating the use of lubrication means to ensure satisfactory emptying forces without any potential harm to the patient.

Parts of the drug formulation which are sensitive to silicone oil or coatings may undergo heterogeneous nucleation at silicone droplet surfaces and may cause an irreversible change in conformation and an increased risk of protein aggregation. Ultimately this can cause an adverse effect on the drug, alter the immunogenic response and reduce its efficiency.

lubrigone’s novel combination of the sealing profile design and special material characteristics comprise a solution with low static and dynamic forces without the traditional need for lubrication or coating of the stopper and container, resulting in a clean injection system.

CONTACT DETAILS

Injecto A/S
Pharmaceutical Packaging
Strandvejen 60, 5.
2900 Hellerup
Denmark

Phone: +45 2785 1000
Email: info@injecto.eu
CVR/Org. No.: 3580 6555

ADVANTAGES

INJECTO can deliver prefillable syringes and syringe components for ready-to-use liquid injectables

Clean injection systems...
Our components are high-precision injection moulded and can be provided for syringe solutions that are lubrication free, coating free, silicone oil free and baked-on silicone free

Feel free to contact INJECTO for more information